Facile functionalization at the C2 position of a highly substituted benzofuran

Shuwen He,Peng Li,Xing Dai, Casey Cameron Mccomas,Chunyan Du,Ping Wang,Zhong Lai,Hong Liu,Jingjun Yin,Paul G Bulger,Qun Dang,Dong Xiao,Nicolas Zorn,Xuanjia Peng,Ravi P Nargund,Anandan Palani

Tetrahedron Letters（2014）

引用 12|浏览24

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摘要

To expedite an SAR study of the C2 position of a highly substituted benzofuran ring system, we developed a method for the preparation of a key precursor, iodide 10. From iodide 10, a diverse set of compounds with different substituents at the C2 position were prepared efficiently.

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关键词

Benzofuran,Substituted 2-iodobenzofuran,Substituted benzofuran-2-ylboronic acid,Suzuki coupling

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