A study of monoelectronic reduction of Artemisinin

Maria Luisa Navacchia,Massimo L Capobianco,Mila D Angelantonio,Giancarlo Marconi

Tetrahedron Letters（2012）

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摘要

The reaction of Artemisinin with solvated electrons (esolv-) generated by radiolytic methods led to the formation of acid 2 as the only detectable product. A possible mechanism leading to the formation of compound 2 is discussed.

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关键词

Artemisinin,Malaria,γ-Radiolysis,Reduction,Alkoxyl radicals

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