OP09.07: Role of 3D ultrasound in the evaluation of the local extent of disease in advanced stage uterine cervical cancer

To analyze the role of 3D ultrasound in the assessment of local extension of disease in locally advanced uterine cervical cancer. Retrospective study of prospectively collected data on 38 women (mean age 49.2 years, range 30-81 years) with histopathological diagnosis of carcinoma of the uterine cervix and clinical advanced stage. All patients were evaluated by 3D transvaginal ultrasound prior to treatment. Lesion size, parametrial, rectal and bladder involvement were evaluated. Staging of the tumors was performed according to the FIGO. In all cases CT, MRI and/or PET was performed as a method of preoperative evaluation as per protocol in our institution. Agreement between 3D ultrasound and MRI/CT for the local extent of disease was assesed by calculating the Kappa index. Three cases were excluded because 3D volume was of poor quality and did not allow adequate analysis. Tumor stages were as follows: 10 IB2 1 IIA, 14 IIB, IIIB 2, 2 and 2 IVA IVB. Tumor size measured by 3D ultrasound was significantly correlated with lesion size measured by CT or MRI (r = 0.603, p = 0.002). Agreement between 3D ultrasound and CT/MRI for parameterial involvement, bladder involvement and rectal involvement was good (kappa = 0.66, percentage of agreement: 83%), very good (kappa = 0.78, percentage of agreement: 97%) and good (kappa = 0.65, percentage of agreement: 94%), respectively. 3D ultrasound has similar performance than CT/ MRI for the evaluation of the local extent of disease in advanced stage uterine cervical cancer.