OP05.01: Does multi‐fetal pregnancy reduction influence perinatal results in twin pregnancies?

Our aim in this study was to compare the perinatal results in multi-fetal pregnancies reduced to twins with the results in non-reduced twin pregnancies. Perinatal results in 85 sets of twins after transabdominal multi-fetal pregnancy reduction (MFPR) of triple and higher-order multiple gestations performed at two different centers of Baskent University were evaluated and compared with the perinatal results in a control group consisting of 173 sets of non-reduced twin pregnancies. The main outcome measures were gestational age at birth, weight of the newborns and weight discordance between the twin pairs. Gestational age at birth appeared to be similar in both groups (presented as mean ± SD, 34.10 ± 3.34 and 34.47 ± 3.24 weeks in the MFPR and control groups respectively, P = 0.456). Weight of the newborns was significantly lower in the MFPR group (presented as mean ± SD, 2111 ± 577 and 2266 ± 632 grams in the MFPR and control groups respectively, P = 0.018). However, weight discordance between the twin pairs didn't show any significant difference between the two groups (presented as mean ± SE, 226 ± 30 and 225 ± 15 grams in the MFPR and control groups respectively, P = 0.360). Our series indicated that, although the gestational age at birth appeared to be similar in twin pregnancies obtained with MPPR and in non-reduced twin pregnancies, those undergoing MFPR reduction were associated with lower birthweight. On the other hand, weight discordance between the twin pairs appeared to be similar in both groups.