144. Physical activity and Insulin-like growth factors in breast cancer survivors: A metaanalysis

Background: Epidemiological data suggest that Insulin-like growth factor 1 (IGF1) and IGF binding protein 3 (IGFBP3) are associated with breast cancer risk, apoptosis and other carcinogenic mechanisms. This metaanalysis evaluated the effects of physical activity in controlling Insulin-like growth factors (IGF1-IGF2) and IGF binding protein-3 (IGFBP3) in patients with breast cancer. Secondary outcomes included insulin, glucose and waist circumference as a body composition measure.