Immunomodulation and nitric oxide restoration by a probiotic and its activity in gut and peritoneal macrophages in diabetic rats

Fabiane R. Maciel,Giovana R. Punaro,Adelson M. Rodrigues,Cristina S.B. Bogsan,Marcelo M. Rogero,Marice N. Oliveira,Margaret G. Mouro,Elisa M.S. Higa

Clinical Nutrition（2016）

引用 27|浏览8

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摘要

•This probiotic improves the inflammatory response in STZ-induced diabetic rats.•Kefir restores the production and release of cytokines and NO in type 1 diabetes.•There is improvement of phagocytic ability of macrophages in diabetic animals by Kefir.•Kefir stimulates the formation of Peyer's patches in small intestine in diabetes.

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关键词

Diabetes,Kefir,Peritoneal macrophages,Cytokines and Nitric oxide

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