Mutual enhancement of IL-2 and IL-7 on DNA vaccine immunogenicity mainly involves regulations on their receptor expression and receptor-expressing lymphocyte generation

Yonghong Zhang,Shuang Liang,Xiujin Li,Liyue Wang,Jianlou Zhang,Jian Xu,Shanshan Huo,Xuebin Cao,Zhenyu Zhong,Fei Zhong

Vaccine（2015）

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摘要

•IL-2 and IL-7 mutually enhanced the immunogenicity of DNA vaccine.•IL-2 can stimulate generation of IL-7 receptor-expressing lymphocytes.•IL-7 can induce IL-2 receptor expression.

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关键词

Interleukin-2,Interleukin-7,Mutual effects,DNA vaccine

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