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Estrogen receptor variant ER-α36 is involved in estrogen neuroprotection against oxidative toxicity

Shikui Han,B Zhao,Xiujuan Pan,Zhiming Song, Jianhua Liu,Y Gong,Minqiang Wang

Neuroscience（2015）

Cited 18|Views21
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Abstract
•ER-α36 is involved in estrogen neuroprotection.•ER-α36 is involved in rapid activation of the PI3K/AKT and MAPK/ERK signaling pathways in estrogen neuroprotective effect.•GPER (GPR30) is not involved in ER-α36-mediated rapid estrogen response.
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AD,BCA,DMEM/F12,DMSO,E2β,ECL,ER,FBS,FITC,GPER,H2O2,MTT,PI,PVDF,siRNA
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