N -Amination of Indoles on Pilot-Plant Scale via Simultaneous and Proportional Metering of Reagents

Franz J Weiberth, Reda G Hanna,George E Lee, Yvonne Polverine, Joseph T Klein

Organic Process Research & Development（2011）

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摘要

The N-amination of indoles on large scale, utilizing a portable Coriolis mass flow metering and pumping system that provides precise dispensing of two reagent streams simultaneously and proportionally, is described.

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关键词

indoles,proportional metering,pilot-plant

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