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1 H, 13 C, 15 N resonance assignments of the extracellular loop 1 domain (ECL1) of Streptococcus pneumoniae D39 FtsX, an essential cell division protein

Biomolecular Nmr Assignments(2015)

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Abstract
FtsX is an integral membrane protein from Streptococcus pneumoniae (pneumococcus) that harbors an extracellular loop 1 domain ( FtsX^ECL1_Spn ) that interacts with PcsB, an peptidoglycan hydrolase that is essential for cell growth and division. Here, we report nearly complete backbone and side chain resonance assignments and a secondary structural analysis of FtsX^ECL1_Spn (residues 47–168 of FtsX) as first steps toward structure determination of FtsX^ECL1_Spn .
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Key words
Bacterial cell wall, Divisome, Peptidoglycan hydrolysis, ABC transporter, Allostery, Extracellular signaling
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