1 H, 13 C, 15 N resonance assignments of the extracellular loop 1 domain (ECL1) of Streptococcus pneumoniae D39 FtsX, an essential cell division protein
Biomolecular Nmr Assignments(2015)
Abstract
FtsX is an integral membrane protein from Streptococcus pneumoniae (pneumococcus) that harbors an extracellular loop 1 domain ( FtsX^ECL1_Spn ) that interacts with PcsB, an peptidoglycan hydrolase that is essential for cell growth and division. Here, we report nearly complete backbone and side chain resonance assignments and a secondary structural analysis of FtsX^ECL1_Spn (residues 47–168 of FtsX) as first steps toward structure determination of FtsX^ECL1_Spn .
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Key words
Bacterial cell wall, Divisome, Peptidoglycan hydrolysis, ABC transporter, Allostery, Extracellular signaling
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