0579: CHA2DS2-VASc score is a predictor of stroke and death in patients with atrial flutter

PurposeThe CHA2DS2-VASc score has been validated to stratify the risk of thromboembolism and accurately predicts the risk of stroke in patient with non-valvular atrial fibrillation. We sought to investigate how accurately this score predicts the risk of stroke and death in patients with atrial flutter.MethodsBetween July 1998 and December 2011, 197 consecutive patients, hospitalised for atrial flutter, were enrolled in the cohort. All patients were followed-up at least 6 months and cardiovascular events recorded. The endpoint was defined as the first occurrence of stroke or death. The Cox analysis was adjusted on warfarin, antiplatelet and antiarrhythmic treatments at discharge.ResultsMean age was 67±13 years and 152 (77%) were men. At baseline, 92 patients (47%) had hypertension, 33 (17%) diabetes, and 10 (5%) had a history of stroke or thromboembolism. CHA2DS2-VASc score was = 0 in 26 (13%), = 1 in 36 (18%), and ≥2 in 135 (69%) patients. Seventy-seven events occurred during a mean follow-up of 4.7±3.7 years. As shown in the Kaplan Meier curves (figure) patients with a CHA2DS2-VASc score ≥2 were at higher risk of stroke or death.The adjusted Cox model showed that a CHA2DS2-VASc score ≥2 was a predictor of risk of stroke or death with a hazard ratio of 2.17 (95%CI 1.21-3.90, p=0.009).ConclusionThese results suggest that a CHA2DS2-VASc score ≥2 is associated with a higher risk of stroke and deaths, at mid-term follow-up, in patients with atrial flutter. Abstract 0579 - Figure: Kaplan-Meier survival curvesFigure optionsDownload full-size imageDownload as PowerPoint slide