0529: Infective endocarditis in patients with ventricular septal defect

In the context of recent change in guidelines for prophylaxis of infective endocarditis (IE), the objective of this study was to assess the features and outcomes of IE in children and adults with non-significant ventricular septal defect (VSD). Methods A retrospective analysis of records of patients with non-significant VSD. Clinical, echocardiographic and microbiological data, and outcos were assessed. Results From 1980 to 2013, 57 IE occurred (1 to 4 per year), in patients aged 14.2±11.3y (med12.1), 29males (51%) and 39 were Conclusion Infective endocarditis impairs prognosis of mild membranous VSD and dental events are the most frequent origin of infection. Preventive surveillance and management of any dental lesion are probably to be emphasized in these patients.