Increased chromosome 16 disomy rates in human spermatozoa associated with recurrent miscarriages
Geburtshilfe Und Frauenheilkunde(2014)
摘要
Introduction: The male contribution in the aetiology of recurrent spontaneous abortions (RSA) is under debate. “Sperm-FISH” data on RSA-males are rare and limited to chromosomes 13,18,21,X and Y. Nevertheless, current data indicate that these patients may have elevated gonosomal disomy rates as well increased cumulative aneuploidy frequencies in spermatozoa.
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关键词
human spermatozoa,recurrent miscarriages,chromosome
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