Removal of Soluble Fms-like Tyrosine Kinase (sFlt-1) by Plasma-Specific Apheresis: A Pilot Study in Women with Severe Preterm Preeclampsia

W Schaarschmidt,R Thadhani,H Hagmann, B Roth, T Kisner,SA Karumanchi,J Wenger, KJ Lucchesi, T Hector,T Lindner,A Fridman,U Thome,A Kribs,M Danner,P Mallmann,H Stepan,T Benzing

Geburtshilfe Und Frauenheilkunde（2015）

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摘要

Soluble Fms-like tyrosine kinase-1 (sFlt-1) is a potential therapeutic target in preeclampsia. We evaluated the safety and efficacy of treating women with very preterm preeclampsia using a plasma-specific dextran sulfate (PSDS) column to remove circulating sFlt-1.

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关键词

kinase,tyrosine,fms-like,plasma-specific

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