Serum pseudocholinesterase and prealbumin concentrations in patients with Crohn's disease

Introduction: The serum pseudocholinesterase was discovered in 1932. It is synthesized in the liver and secreted into the circulation as a sialed glycoprotein. The pseudocholinesterase consists of four molecular forms as C1, C2, C3 and C4 according to their electrophoretic mobility. This protein is involved in the pathogenesis of several disease, but its true biological function is unknown. It is an excellent indicator of functional liver mass in cirrhosis. Pre-albumin is synthesized in the liver and in the mucosa of the gastrointestinal tract. It is a human negative acute phase protein which represents mainly the protein synthesis of the liver.