Electroanalysis of Benazepril Hydrochloride Antihypertensive Drug Using an Ionic Liquid Crystal Modified Carbon Paste Electrode

Electroanalysis of benazepril HCl was successful using a carbon paste electrode modified with an ionic liquid crystal (1-butyl-1-methylpiperidinium hexafluorophosphate) in presence of sodium dodecyl sulfate. The electrode performance was compared to ionic liquids (1-n-hexyl-3-methyl imidazolium tetrafluoroborate and 1-butyl-4-methyl pyridinium tetrafluoroborate). Electrochemical determination of benazepril HCl was in the linear dynamic range of 8.89 x 10(-7) to 1.77 x 10(-5) molL(-1) (correlation coefficient 0.999) and LOD 7.17 x 10(-9) molL(-1). benazepril HCl was determined using this sensor in presence of urine metabolites such as uric acid, ascorbic acid. Binary mixtures of dopamine/benazepril and amlodipine/benazepril were also determined successfully.