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Liver involvement in juvenile systemic lupus erythematosus (SLE)

Generosa Mariniello,Giustina Russo,Raffaella Carlomagno, Rosalba Vitale,Maria Alessio

Pediatric Rheumatology(2011)

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Abstract
Abnormal liver tests are common among adult patients with systemic lupus erythematosus (SLE). The most common cause is drug-induced hepatitis, while mild, predominantly lobular, but sometimes also portal and periportal-hepatitis reflecting SLE activity, is another possibility. Little is known about liver disease in juvenile SLE patients although mild transient liver enzyme abnormalities are noted in up to 25%.
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Key words
Systemic Lupus Erythematosus, Liver Disease, Liver Enzyme, Systemic Lupus Erythematosus Patient, Liver Dysfunction
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