Difficultés d’interprétation des gammapathies monoclonales de découverte fortuite : cas d’une gammapathie transitoire au cours d’un syndrome inflammatoire important

The discovery of a monoclonal immunoglobulin is usually witnessed a malignant lymphoproliferative disease, but sometimes it is a transient event during viral, bacterial or fungal infections and during an inflammatory syndrome. Achieving electrophoresis performed in an elderly patient aged 55 with anemia to 63 g/L hemoglobin showed a consistent profile with intense inflammatory syndrome and chronic atypical with elevated C-reactive protein (CRP) greater than 300 mg/L (normal values: 0-8 mg/L) associated with the presence of two thin appearance monoclonal migrating bands in gamma position. Achieving immunofixation showed IgM kappa monoclonal confirmed by using betamercaptoethanol (BME). Radiological findings, hematological, revealed nothing. The recovery of blood away from the inflammation on another sample report presented a CRP at 5 mg/L and a subnormal profile electrophoresis and immunofixation revealed nothing. The comparison of the results of biochemical investigations, haematological and clinical and radiological control of the electrophoretic profile of a remote inflammatory syndrome to exclude cases of transient gammopathies.