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Probing the Xeno-Oestrogenic Impact of Sediment Cores Contaminated by the Pulp and Paper Industry: Induction of Aromatase Cyp19a1b in Late Larval Zebrafish

Journal of soils and sediments(2014)

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Abstract
Chemicals in effluents from the wood industry have been widely identified as sources of contamination affecting endocrine function in aquatic animals. This study examined the changes in transcript levels of key biomarkers, cytochrome P450 1A (cyp1a), brain aromatase (cyp19a1b) and vitellogenin 1 (vtg1), in late larval zebrafish exposed to sediment cores from areas upstream and downstream (two distances) from a pulp and paper mill in Finland.
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Key words
cyp19a1b,Oestrogenicity,PPME,qRT-PCR,vtg1,Whole-sediment bioassay,Zebrafish
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