A HIGHLY BIOAVAILABLE OMEGA-3 FREE-FATTY ACID REDUCES NON-HIGH DENSITY LIPOPROTEIN CHOLESTEROL IN HIGH-RISK PATIENTS TREATED WITH A STATIN AND RESIDUAL HYPERTRIGLYCERIDEMIA (ESPRIT TRIAL)

Kevin C Maki,David G Orloff,Stephen J Nicholls,Richard L Dunbar,Eli M Roth,Danielle Curcio,Judith Johnson,Douglas Kling,Michael H Davidson

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2013）

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Abstract

At least 4 grams of prescription omega-3 ethyl esters (EE) are required to lower non-high density lipoprotein cholesterol (non-HDL-c) in patients treated with a statin with triglycerides (TG) between 200-499 mg/dL. Omega-3 EE require hydrolysis to free-fatty acids (FFA) by pancreatic lipases for

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Key words

cholesterol,statin,residual hypertriglyceridemia,free-fatty,non-high,high-risk

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