GW25-e1409 CKIP-1 can regulate physiological cardiac hypertrophy through inhibition of HDAC4 phosphorylation

Ling Shukuan,Zhang Pengfei,Li Yuheng,Zhao Dingsheng,Sun Weijia,Xu Zi,Zhong Guohui,Li Qi,Song Jinping,Li Yinghui,Li Yingxian

Journal of the American College of Cardiology（2014）

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摘要

Mechanical stress on the heart can lead to different results. Physiological stimuli such as exercise cause adaptive cardiac hypertrophy characterized by a normal cardiac structure and normal or enhanced cardiac function. Pathological stimuli such as sustained cardiac pressure overload cause

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