GW25-e5274 Lycopene protects endoplasmic reticulum stress-induced apoptosis against neonatal mouse cardiomyocytes hypoxia/reoxygenation injury

Hu Houxiang,Yu Zhengping,Zhang Shuang,Xu Lei,Zhou Zhou,Chen Bin,Xu Jiqian

Journal of the American College of Cardiology（2014）

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摘要

Endoplasmic reticulum (ER) stress induced apoptosis has been implicated as a critical cause in the pathogenesis of myocardial ischemia reperfusion (I/R) injury. Our previous studies demonstrated that lycopene exhibits great pharmacological potential in protecting against the I/R-injury, but whether

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关键词

endoplasmic reticulum stress,endoplasmic reticulum,apoptosis,neonatal mouse

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