Synthetic Studies towards Optically Active 13-Oxyingenol via Asymmetric ­Cyclopropanation

The enantioselective synthesis of a seven-membered enone compound, the key intermediate of our previous synthesis of the inside-outside framework of 13-oxyingenol in racemic form, was achieved by using asymmetric cyclopropanation and reductive deoxygenation as key steps.