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Vanishing configurations in network dynamics with asynchronous updates

PROCEEDINGS OF THE AMERICAN MATHEMATICAL SOCIETY(2014)

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摘要
We consider Boolean dynamics for biological networks where stochasticity is introduced through asynchronous updates. An exact method is given for finding states which can reach a steady state with positive probability, and a method is given for finding states which cannot reach other steady states. These methods are based on computational commutative algebra. The algorithms are applied to dynamics of a cell survival network to determine node assignments that exclude termination in a cancerous state.
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关键词
Asynchronous network,basin of attraction,Boolean network,Groebner basis,Markov chain
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