Stereochemistry analysis and comparison of two C(3)-alkyl substituted cyclohexonedicarboxylates with their C(3)-aryl substituted analogues

Two representative C(3)-alkyl substituted cyclohexonedicarboxylates (4a and 4b) were synthesized and their conformational features were investigated by single crystal X-ray crystallography for the first time. These stereochemistry results of 4a and 4b were compared with those obtained from the earlier research of C(3)-aryl substituted analogues (1–3).