Effects of histone methyltransferase inhibitor 3-Deazaneoplanocin (DZNep) on rhabdoid tumor cell lines
Klinische Padiatrie（2012）
Abstract
Rhabdoid tumors (RT) are highly aggressive pediatric tumors which arise in brain, heart, kidney, liver and other soft tissues. Although the prognosis of RT patients has improved, it still remains poor due to an initial response to conventional chemotherapy followed by resistance.
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Key words
histone methyltransferase inhibitor,dznep,tumor
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