1209 THE ROLE OF PROSTATE BIOPSY AFTER SALVAGE CRYOSURGERY FOR CLINICALLY LOCALIZED PROSTATE CANCER

You have accessJournal of UrologyProstate Cancer: Localized1 Apr 20131209 THE ROLE OF PROSTATE BIOPSY AFTER SALVAGE CRYOSURGERY FOR CLINICALLY LOCALIZED PROSTATE CANCER Einar Sverrisson, Huy Nguyen, Timothy Kim, and Julio Pow-Sang Einar SverrissonEinar Sverrisson Tampa, FL More articles by this author , Huy NguyenHuy Nguyen Tampa, FL More articles by this author , Timothy KimTimothy Kim Tampa, FL More articles by this author , and Julio Pow-SangJulio Pow-Sang Tampa, FL More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2563AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Salvage cryosurgery is an option for men who have failed primary treatment for clinically localized prostate cancer. Many urologists do not include post-treatment biopsy in their protocols but choose to follow PSA levels instead. We were interested in correlating perioperative tumor characteristics with postoperative biopsy results in men who underwent salvage cryosurgery at a single institution. METHODS A retrospective review was performed of all men treated with salvage cryosurgery at our institution between 2001 and 2011. Perioperative PSA levels, Gleason score and number of positive cores were obtained and postoperative biopsy results were reviewed. Patients were stratified according to D'Amico's risk classification system to low, intermediate or high risk groups. RESULTS 72 men were treated with salvage cryosurgery and 65% (47/72) underwent postoperative biopsy on average 6 months after their treatment. 15% were found to have persistent tumor. Preoperative PSA level (3.6 vs 4.1, P=0.788) and postoperative nadir PSA level (1.66 vs 0.7, P=0.1), Gleason score (7.1 vs 7.2, P=0.86) and number of positive preoperative biopsy cores (4.4 vs 4.4, P= 0.96) did not predict results of postoperative biopsy. No significant difference was noted when stratified for different risk groups. CONCLUSIONS Our findings demonstrate that 15% of men have viable tumor after salvage cryosurgery. Preoperative tumor characteristics, risk group category, or postoperative PSA nadir level do not predict tumor persistence on postoperative biopsy. Men treated with salvage cryosurgery for recurrent prostate cancer should undergo postoperative biopsy to determine the efficacy of treatment. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e495-e496 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Einar Sverrisson Tampa, FL More articles by this author Huy Nguyen Tampa, FL More articles by this author Timothy Kim Tampa, FL More articles by this author Julio Pow-Sang Tampa, FL More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...