1059 RISK FACTORS FOR SEPTIC SHOCK IN ACUTE PYELONEPHRITIS WITH URETERAL CALCULI

You have accessJournal of UrologyInfections/Inflammation of the Genitourinary Tract: Kidney & Bladder (I)1 Apr 20131059 RISK FACTORS FOR SEPTIC SHOCK IN ACUTE PYELONEPHRITIS WITH URETERAL CALCULI Phil Hyun Song, Yoon Seob Ji, Yeong Uk Kim, Hong Seok Shin, Young Hwii Ko, Hee Chang Jung, and Ki Hak Moon Phil Hyun SongPhil Hyun Song Daegu, Korea, Republic of More articles by this author , Yoon Seob JiYoon Seob Ji Daegu, Korea, Republic of More articles by this author , Yeong Uk KimYeong Uk Kim Daegu, Korea, Republic of More articles by this author , Hong Seok ShinHong Seok Shin Daegu, Korea, Republic of More articles by this author , Young Hwii KoYoung Hwii Ko Daegu, Korea, Republic of More articles by this author , Hee Chang JungHee Chang Jung Daegu, Korea, Republic of More articles by this author , and Ki Hak MoonKi Hak Moon Daegu, Korea, Republic of More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.645AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Acute pyelonephritis (APN) associated with ureteral calculi can progress to the septic shock that can be lethal if it is more aggravated. We investigated risk factors for septic shock in patients with sepsis due to APN associated with ureteral calculi. METHODS From January 2005 to June 2012, a total of 49 patients with sepsis due to APN associated ureteral calculi were enrolled in this study and divided into two groups: with (n=15) or without (n=34) septic shock. We retrospectively investigated the clinical characteristics (age, sex, hospital stay (days), the past medical history, history of ureteral calculi), stone size and location, laboratory data, and radiologic finding of these patients. RESULTS The mean age was 67.2 years and the mean hospital stay was 11.8 days. 19 patients (38.8%) were managed by percutaneous nephrostomy and 11 patients (22.4%) were associated with history of ureteral calculi. In the univariate analysis, old age(≥ 60 years), hypertension, thrombocytopenia (≤ 100,000/ul), positive blood culture, hypoalbuminemia (≤ 3.0 g/ul), elevated serum creatinine levels(≥ 1.5 g/dl), elevated serum procalcitonin levels (≥ 0.5 ug/L) were correlated with septic shock (p<0.05). Multivariate logistic regression analysis showed that increased procalcitonin (≥ 0.5ug /L) and positive blood culture were independent risk factor associated with septic shock (p=0.042, p=0.021). CONCLUSIONS Our study revealed that elevated serum procalcitonin levels (≥ 0.5 ug/L) and positive blood culture were independent risk factors for septic shock in patients with sepsis due to APN associated with ureteral calculi. Thus, we suggest that Intensive care may be recommended to prevent fatal outcomes in patients with these factors. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e434 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Phil Hyun Song Daegu, Korea, Republic of More articles by this author Yoon Seob Ji Daegu, Korea, Republic of More articles by this author Yeong Uk Kim Daegu, Korea, Republic of More articles by this author Hong Seok Shin Daegu, Korea, Republic of More articles by this author Young Hwii Ko Daegu, Korea, Republic of More articles by this author Hee Chang Jung Daegu, Korea, Republic of More articles by this author Ki Hak Moon Daegu, Korea, Republic of More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...