PD21-03 PROSTATE ACTIVITY IN MEN WITH PARKINSON′S DISEASE ARE NOT DIFFERENT COMPARED TO AGE-MATCHED CONTROL GROUP: A PROSPECTIVE, CASE CONTROLLED MULTICENTRE STUDY

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology & Natural History1 Apr 2014PD21-03 PROSTATE ACTIVITY IN MEN WITH PARKINSON′S DISEASE ARE NOT DIFFERENT COMPARED TO AGE-MATCHED CONTROL GROUP: A PROSPECTIVE, CASE CONTROLLED MULTICENTRE STUDY Ho Gyun Park, Oh Seok Ko, Min Woo Cheon, and Young Beom Jeong Ho Gyun ParkHo Gyun Park More articles by this author , Oh Seok KoOh Seok Ko More articles by this author , Min Woo CheonMin Woo Cheon More articles by this author , and Young Beom JeongYoung Beom Jeong More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.1680AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail Introduction and Objectives As the population is aging, the burden of neurological disorders is increasing but access to care is limited. Especially, considerable number of patients with Parkinson′s Disease (PD) suffers from gait disturbance as well as lower urinary tract symptoms (LUTS). There were no reports that have evaluated prostate activity of patients with PD. We prospectively evaluated the prostate volume (PV) and serum prostate-specific antigen (PSA) level to assess prostate activity in men with PD. Methods From May 2009 to January 2012, 60 PD patients and 60 age-matched non-PD patients with LUTS were enrolled at three centers. All subjects including PD as well as non-PD patients had LUTS at presentation. We measured the prostate volume (PV) using a transrectal ultrasonography and checked serum prostate-specific antigen (PSA) level in patients with PD as well as in those with as LUTS but not PD as age-matched control group, and then compared the two groups′ data. Results The mean ages of both groups were 71.37±7.36 in PD and 70.85±6.31 in non-PD (p=0.651). There were no significant statistical differences between two groups in total PV (28.56±14.59 in PD vs. 29.21±10.41 in non-PD, p=0.727), transition zone PV (12.72±8.76 vs. 12.73±6.68, p=0.993) and total serum PSA (1.88±2.80 vs. 2.01±2.02, p=0.759). Conclusions Our data show that a neurologic lesion causing PD does not affect prostate activity. In common with normal aged men, therefore, regular PSA check-up in men with PD will be needed as the prostate cancer screening whether they have LUTS or not. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e606-e607 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Ho Gyun Park More articles by this author Oh Seok Ko More articles by this author Min Woo Cheon More articles by this author Young Beom Jeong More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ...