2310 kidney donor radiation exposure prior to transplantation

The Journal of Urology(2013)

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You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation, Renal Vascular Surgery (II)1 Apr 20132310 KIDNEY DONOR RADIATION EXPOSURE PRIOR TO TRANSPLANTATION David Culpepper, Caroline Wallner, Gene Huang, Steven Engebretsen, Gaudencio Olgin, Don Arnold, Jason Smith, and D. Duane Baldwin David CulpepperDavid Culpepper Loma Linda, CA More articles by this author , Caroline WallnerCaroline Wallner Loma Linda, CA More articles by this author , Gene HuangGene Huang Loma Linda, CA More articles by this author , Steven EngebretsenSteven Engebretsen Loma Linda, CA More articles by this author , Gaudencio OlginGaudencio Olgin Loma Linda, CA More articles by this author , Don ArnoldDon Arnold Loma Linda, CA More articles by this author , Jason SmithJason Smith Loma Linda, CA More articles by this author , and D. Duane BaldwinD. Duane Baldwin Loma Linda, CA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2251AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES During the evaluation of potential kidney donors, every effort is made to protect these patients from experiencing unnecessary harm. Thus it is important for donor surgeons to understand the potential risks and radiation dosages associated with donor imaging studies. The purpose of this study is to characterize living donor radiation exposure. METHODS A retrospective review of 363 donor nephrectomy patients evaluated over a 12-year period was performed. By protocol, each donor received a chest x-ray, nuclear renal scan, and 3-phase CT of the abdomen. Female patients greater than 40 years of age received screening mammograms. Patients with a smoking history underwent CT of the chest. Estimated effective dose (EED) was calculated for CT by multiplying the dose-length product (DLP) by standard conversion factors. EED for nuclear renal scans, mammograms, and chest x-rays were calculated using published values. Image modality with total EED and EED averages with yearly time points were correlated using Pearson's correlation. RESULTS Of the 363 donors, complete radiation parameters including DLP were available in 154 patients. Mean total effective dose was 29.4 mSv (SD 13.4), with 83.7% of exposure resulting from 3-phase CT of the abdomen (Table 1). A subset of donors evaluated (42.7%) received ≥ 30 mSv, while 4.8% received ≥ 50 mSv. Average radiation exposure decreased by 30.4% in the latest 6 years of the study period (correlation = -0.90) with changes in imaging protocol. CONCLUSIONS Renal donors are exposed to significant levels of ionizing radiation with a mean that approaches the maximum occupational radiation exposure for nuclear workers of 30 mSv. Knowledge of the radiation exposure received by donors may allow transplant centers to more accurately counsel donors regarding risk and tailor imaging protocols to maximize patient safety. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e947 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information David Culpepper Loma Linda, CA More articles by this author Caroline Wallner Loma Linda, CA More articles by this author Gene Huang Loma Linda, CA More articles by this author Steven Engebretsen Loma Linda, CA More articles by this author Gaudencio Olgin Loma Linda, CA More articles by this author Don Arnold Loma Linda, CA More articles by this author Jason Smith Loma Linda, CA More articles by this author D. Duane Baldwin Loma Linda, CA More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ...
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关键词
radiation exposure prior,transplantation,donor,kidney
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