Elevated Plasma Active Matrix Metalloproteinase 9 Level is Associated with Increased Diastolic Dysfunction Independent of Hypertension and Left Ventricular Hypertrophy in Patients with Coronary Artery

Background: This study aimed to investigate whether endogenous active levels of matrix metalloproteinases-9 (MMP-9) or tissue inhibitor of metalloproteinases-1 (TIMP-1) were related to indices of diastolic dysfunction (DD) in the setting of contemporary treatment of coronary artery disease (CAD).