Association of CDX1 binding site of periostin gene with bone mineral density and vertebral fracture risk
Osteoporosis International(2012)
Abstract
Periostin (POSTN) as a regulator of osteoblast differentiation and bone formation may affect susceptibility to osteoporosis. This study suggests POSTN as a candidate gene for bone mineral density (BMD) variation and vertebral fracture risk, which could better our understanding about the genetic pathogenesis of osteoporosis and will be useful in clinic in the future.
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Key words
Association,BMD,CDX1,Periostin,Vertebral fracture
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