Papular Purpuric Gloves and Socks Syndrome Due to Parvovirus B19 Infection: A Case Report and Review

Papular purpuric gloves and socks syndrome (also known as gloves and socks syndrome) is a relatively newly described viral dermatosis with unique characteristics. These characteristics typically include an erythematous, papular, or petechial rash and edema in an acral distribution, often with associated mucosal lesions, arthralgias, and fever. We present a case of papular purpuric gloves and socks syndrome in a 46-year-old patient with acute parvovirus B19 infection, review the descriptive literature, and summarize our evolving understanding of this disease.