Molecular cloning and expression studies of the adapter molecule myeloid differentiation factor 88 (MyD88) in turbot (Scophthalmus maximus)
Developmental & Comparative Immunology(2015)
摘要
•A full-length cDNA of MyD88 was cloned from turbot.•MyD88 transcripts distributed ubiquitously with higher levels detected in lymphomyeloid-rich tissues.•MyD88 was up-regulated by LPS, CpG-ODN and TRBIV in immune and non-immune organs.•The induction by CpG-ODN was strongest and initiated earliest.
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关键词
MyD88,Scophthalmus maximus,LPS,CpG-ODN,TRBIV,Gene expression
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