MicroRNA 206 is associated with longer overall survival and platinum sensitivity in serous epithelial ovarian cancer

A Jewell,Karen M Watters, A Mitra,Riyue Bao,C Y Chiang, M Curtis,Joao Marcus Oliveira Andrade,D S Yamada,Ernst Lengyel

Gynecologic Oncology（2014）

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摘要

Objectives: Most women with high-grade serous epithelial ovarian cancer (EOC) eventually develop platinum-resistant disease. MicroRNAs (miRNAs) are pleiotropic and regulate many biologic processes. Our objective was to identify and validate miRNAs associated with platinum resistance in EOC.

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serous epithelial ovarian cancer

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