Comprehensive characterization of cardiac morphology and function in adult patients with phenylketonuria using CMR

Jan-Hendrik Hassel,Nikolaus Tilling, Lenka Bosanska,Bernhard Schnackenburg,Daniel Messroghli,Alexander Berger,Rolf Gebker,Christopher Schneeweis,Eckart Fleck,Ursula Plöckinger,Sebastian Kelle

Journal of Cardiovascular Magnetic Resonance（2014）

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摘要

Background Phenylketonuria (PKU) is one of the most common inherited metabolic disorders. The molecular pathway of neurological damage is not yet sufficiently understood. To date, there is a lack information about cardiac involvement related to the disease. This study aims to characterize cardiac morphology and function in adult patients with PKU using cardiovascular magnetic resonance (CMR).

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关键词

Cardiovascular Magnetic Resonance,Left Ventricular Mass,Cardiac Involvement,Left Ventricular Mass Index,Phenylketonuria

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