Tu1175 Incidence and Characteristics of Intestinal and Extraintestinal Cancers in Patients With Inflammatory Bowel Disease: A Population-Based Study

(p = 0.013) during follow-up of the cohort. No statistical significance was obtained regarding the need for biological therapy or surgery. Statistically significant association between smoking and need for hospitalization was also found in CD (p = 0.004). There is also a significant association between younger age at diagnosis and biological therapy need (p = 0.022) and between B3 pattern and need for immunomodulatory therapy (p = 0.009). The B1 pattern was associated with less hospitalization (p = 0.049) and less need for surgery (p = 0.018). For UC no statistically significant association between the independent variables of the patients, disease phenotype and therapeutic needs was found. Conclusions: In our hospital area of southern Spain incidence rates are similar to other areas of southern Europe. However Greater incidence of Crohn’s disease with respect to UC is described. Crohn’s disease requires more aggressive therapy than CU (immunomodulators and surgery). An early age at diagnosis is associated with greater need for biologic therapy.