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Mo1706 Inhibitory Effects of an Orally Active Small Molecule Alpha4beta1/ Alpha4beta7 Integrin Antagonist, TRK-170, on Spontaneous Colitis in HLAB27 Transgenic Rats

Hiroe Hirokawa,Yoko Koga,Rie Sasaki,Sunao Hara,Hiroyuki Meguro,Mie Kainoh

Gastroenterology（2014）

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Abstract
Methods: Colitis was induced in immunodeficient SCID mice by the adoptive transfer of CD4 +
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Key words
spontaneous colitis,hlab27 transgenic rats,inhibitory effects
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