Cross-linking as a tool for enhancement of transfection efficiency of cationic vectors

E D Maximova,E B Faizuloev,Alexandra Nikonova,S L Kotova,A B Solov Eva,Vladimir A Izumrudov,E A Litmanovich,Elena V Kudryashova,N S Meliknubarov

European Polymer Journal（2015）

引用 5|浏览10

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摘要

•Nanogels produced in reverse micelles exhibit extremely narrow size distribution.•Nanogels with 2% of the cross-linker produce the most compact complexes with DNA.•The same nanogels manifest the highest transfection efficacy.

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关键词

Nanogels,Degree of cross-linking,Transfection,siRNA

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