The effect of gliquidone on KATP channels in pancreatic β-cells, cardiomyocytes, and vascular smooth muscle cells
Diabetes Research and Clinical Practice（2015）
Abstract
•Among drugs tested, gliquidone had moderate affinity to β-cells.•Gliquidone had low affinity to cardiomyocytes and VSMCs.•Thus, gliquidone is a highly selective SUR secretagogue to β-cells.
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Key words
Gliquidone,ATP-sensitive potassium channel,Patch clamp technique,HIT-T15 cell,Cardiomyocyte,Vascular smooth muscle cell
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