Synthesis of N -aryl benzamides containing pharmacophoric tyrosine kinase inhibitor fragments

E. V. Koroleva,Zh. V. Ignatovich,K. N. Gusak,A. L. Ermolinskaya,Yu. V. Sinyutich

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY（2015）

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摘要

New N -aryl 4-(arylaminomethyl)benzamides containing pharmacophoric heterocyclic fragments have been synthesized from 2-arylaminopyrimidine, 1-methylpiperazine, and morpholine derivatives and substituted benzoic acids.

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关键词

Piperazine,Benzamide,Raney Nickel,Amino Amide,Benzotriazolyl

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