First Analysis Of Relation Between Cyp2c19 Genotype And Platelet Function In Ticagrelor Versus Clopidogrel Treated Patients: Results From The Onset/Offset And Respond Studies

Paul A. Gurbel, Kevin Bliden,Robert F. Storey,Cheryl Wei,Martin Armstrong,Kathleen Butler,Udaya S. Tantry

Circulation（2010）

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摘要

Background: CYP2C19 genotype influences platelet aggregation (PA) and clinical outcomes in patients treated with clopidogrel (C), however its relation to platelet function in ticagrelor (T) treated...

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Genetics, Pharmacology, Thrombosis

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