Abstract 16161: Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: Good for Any Age?

Introduction: Alcohol septal ablation (ASA) is an accepted non-surgical therapy for septal reduction in patients with medically refractory Hypertrophic Obstructive Cardiomyopathy (HOCM). We sought to determine the relative efficacy of ASA across ages. Methods: We divided 405 consecutive patients treated with ASA at our institution into age groups of those Results: Compared with the patients 65 compared with those 45-64 years old (22.5% vs 9.6%, p=0.004; Figure 1B). All groups had a significant reduction in gradients from baseline (Figure 1C). At 3 months, the average NYHA score was lower in the middle age group compared with those Conclusions: Despite a patient population with more comorbidities at baseline and a higher rate of procedural complications, older patients showed a sustained improvement in symptoms and gradients similar to their younger counterparts.