Abstract 19326: Microrna Regulating Protein Bicc1 Causes Dilated Cardiomyopathy Through Modulation of Polycystin-2

Hisato Yagi,Xiaoqin Liu,Bishwanath Chatterjee,You Li, Ashok Srinivasan,Adrew Kim, Deborah Farkas,Richard Francis,Jacqueline Ho,Kimimasa Tobita,Cecilia W. Lo

Circulation（2012）

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摘要

An ENU-induced mutation in the RNA binding protein Bicc1 was recovered in a mutant named Destro. Destro exhibits complex congenital cardiovascular defects (CHD) associated with heterotaxy, with som...

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