Acquired Resistance to Aromatase Inhibitors is Paired With Hyper-activation of Akt/mTor Pathway in New Cellular Models of Hormone-dependent Breast Cancer
European Journal of Cancer（2012）
摘要
S239ligands can be further uncoupled.This opens the possibility that some ligands can trigger degradation alone, in the absence of transactivation.
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关键词
aromatase inhibitors,breast cancer,akt/mtor pathway,hyper-activation,hormone-dependent
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