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Multicomponent systems with cyclodextrins and hydrophilic polymers for the delivery of Efavirenz

Alexandre Couto Carneiro Vieira,Danilo Augusto Ferreira Fontes,Luise Lopes Chaves,Lariza Darlene Santos Alves,José Lourenço de Freitas Neto,Monica Felts de La Roca Soares,Jose L. Soares-Sobrinho,Larissa Araújo Rolim,Pedro José Rolim-Neto

Carbohydrate Polymers（2015）

Cited 32|Views2
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Abstract
•Increase the aqueous solubility of Efavirenz.•Formation of an inclusion complex with cyclodextrin.•Formation of ternary systems with cyclodextrins and hydrophilic polymers.•Characterizations of the ternary system in the solid state by SEM, DSC, TG, XRD, dissolution profile and FT-IR.
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Key words
Low solubility,Polymers,Ternary systems,Inclusion complex,Delivery systems
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