Diallyl trisulphide inhibits adipogenesis in 3T3-L1 adipocytes through lipogenesis, fatty acid transport, and fatty acid oxidation pathways

Journal of Functional Foods（2015）

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摘要

•DATS decreases intracellular triglyceride and GPDH activity in 3T3-L1 adipocytes.•DATS increases adiponectin production in 3T3-L1 adipocytes.•DATS inhibits adipogenesis in 3T3-L1 adipocytes.•DATS regulates gene levels of lipogenesis, lipolysis, and adipokines.

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关键词

ACC,alliin,aP2,C/EBPα,DAS,DADS,DATS,DEX,DMEM,DMSO,FAS,GPDH,IBMX,INS,LPL,MCP-1,OROSM,OSC,PAI-1,PGC-1β,PPARγ,SAC,UCP1

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