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Identification of anti-allergic lactic acid bacteria that suppress Ca2+ influx and histamine release in human basophilic cells

Kaoru Fujii,Tsukasa Fujiki,Ayaka Koiso,Kozue Hirakawa,Makiko Yamashita,Takashi Matsumoto,Takanori Hasegawa,Fumiki Morimatsu,Yoshinori Katakura

Journal of Functional Foods（2014）

Cited 4|Views5
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Abstract
•We screened for anti-allergic lactic acid bacteria (LABs) using KU812F.•Specific LABs suppressed the Ca2+ influx triggered by IgE crosslinking.•Specific LABs suppressed histamine release triggered by Ca2+ influx.•Five candidate anti-allergic LAB strains suppressed both the increase.
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Th2,IL,FcεRI,LAB,GM-CSF,IFN,PBS,HHBS,HDC,TFN,PMA
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