Aqueous extracts of hulled barley containing coumaric acid and ferulic acid inhibit adipogenesis in vitro and obesity in vivo

•An aqueous extract from hulled barley (AHB) was effective in anti-adipogenesis.•Roasting condition affected anti-adipogenic activities of AHB.•Aqueous extracts of hulled barley prevented obesity in obese C57BL/6 mice.•Oral administration of AHB prevented weight gain in ovariectomized female rats.•Coumaric acid and ferulic acid can mediate anti-adipogenic actions of AHB.