SYNTHESIS, CHARACTERIZATION, THERMAL AND ANTIBACTERIAL STUDY OF A NOVEL SULFONAMIDE DERIVATIVE, W-[(E)-PYRIDIN-3-YLMETHYLIDENE]BENZENESULFONAMIDE, AND ITS CO(II), CU(II) AND ZN(II) COMPLEXES
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY(2013)
Abstract
The novel aromatic sulfonamide ligand, N-[(E)-pyridin-3-ylmethylidene] benzenesulfonamide (PMBS) was synthesized along with its Cu(II), Co(II) and Zn(II) complexes of MLCl2 type. The characterization of the complexes and the ligand was done by physical methods like elemental analysis, UV-VIS spectra, H-1-NMR, IR and conductance studies. Additionally, the thermal degradation pattern was examined by TG/DT analysis. Antimicrobial activities are studied with both gram negative Pseudomonas aeruginosa, Salmonella typhi, Eschericia coli and gram positive bacteria Bacillus subtilus, Staphylococcus aureus, Staphylococcus epidermis, Streptococcus pneumonia.
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Key words
N-[(E)-pyridin-3-ylmethylidene] benzenesulfonamide (PMBS),Escherichia coli,Salmonella typhi,Bacillus subtilus,Staphylococcus aureus
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